Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | PTAFR | P25105 | 4/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979929 | 1.00 | CYP3A4 (0.39) | CYP3A4PTAFRADAMTS4POLBHPGD | |
| SCHEMBL7979925 | 1.00 | CYP3A4 (0.39) | CYP3A4PTAFRADAMTS4POLBHPGD | |
| SCHEMBL7976666 | 0.93 | CYP3A4 (0.39) | CYP3A4PTAFRADAMTS4POLBHPGD | |
| SCHEMBL7976671 | 0.93 | CYP3A4 (0.39) | CYP3A4PTAFRADAMTS4POLBHPGD | |
| SCHEMBL7979810 | 0.90 | HTT (0.39) | PTAFRADAMTS4POLBHPGDHTT | |
| SCHEMBL7979812 | 0.90 | HTT (0.39) | PTAFRADAMTS4POLBHPGDHTT | |
| SCHEMBL7978426 | 0.89 | CYP3A4 (0.38) | CYP3A4PTAFRADAMTS4GRM2NAMPT | |
| SCHEMBL7978428 | 0.89 | CYP3A4 (0.38) | CYP3A4PTAFRADAMTS4GRM2NAMPT | |
| SCHEMBL7966622 | 0.88 | PTAFR (0.39) | PTAFRADAMTS4POLBHPGDHTT | |
| SCHEMBL7966624 | 0.88 | PTAFR (0.39) | PTAFRADAMTS4POLBHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | claimed |