Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.88 |
| ▸ | ACACB | O00763 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184973 | 1.00 | POLB (0.88) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL9966795 | 1.00 | POLB (0.88) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL15022586 | 0.85 | ACACB (0.73) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL15022588 | 0.85 | ACACB (0.73) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL256318 | 0.83 | ACACB (1.00) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL19200906 | 0.83 | ACACB (0.71) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL807909 | 0.83 | ACACB (0.71) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL15038846 | 0.83 | RECQL (0.87) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL14314483 | 0.83 | RECQL (0.87) | POLBACACBHPGDSMN1; SMN2GAA | |
| SCHEMBL19884283 | 0.83 | RECQL (0.87) | POLBACACBHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844299-B | Desinsection aryl-pyrrolidine alkane | BAYER CROPSCIENCE AG (DE) | 2016-03-30 | — | — | CN | disclosed |
| CN-104955328-A | Methods of controlling insects | SYNGENTA PARTICIPATIONS AG | 2015-09-30 | — | — | CN | disclosed |
| CN-104602526-A | Methods of controlling insects | SYNGENTA PARTICIPATIONS AG | 2015-05-06 | — | — | CN | disclosed |
| CN-104582483-A | Methods of soil pest control | SYNGENTA PARTICIPATIONS AG | 2015-04-29 | — | — | CN | disclosed |
| CN-103282347-B | Pesticidal arylpyrrolidines | BAYER IP GMBH | 2015-04-01 | — | — | CN | disclosed |
| EP-2519499-B1 | PESTICIDAL ARYLPYRROLIDINES | BAYER IP GMBH (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-8536201-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-17 | — | — | US | disclosed |
| CN-103282347-A | Pesticidal arylpyrrolidines | BAYER IP GMBH | 2013-09-04 | — | — | CN | disclosed |
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| CN-102844299-A | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2012-12-26 | — | — | CN | disclosed |
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| EP-2519499-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011080211-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | DDT, CYP4X1, CHRM2 | POLB 4785/4885ACACB 4402/4885HPGD 2141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.