Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.66 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.66 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.66 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982088 | 0.94 | GRIA1 (0.64) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7987270 | 0.89 | GRIA1 (0.62) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6785446 | 0.80 | GRIA1 (0.74) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6784036 | 0.78 | GRIA1 (0.69) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8811122 | 0.77 | GRIA1 (0.68) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6783780 | 0.76 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6789407 | 0.75 | GRIA1 (0.67) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL6784471 | 0.74 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7980695 | 0.74 | GAA (0.47) | — | |
| Hydrochloric Acid SCHEMBL8807575 | 0.74 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057313-A | TREATING CENTRAL NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 2000-05-02 | — | — | US | claimed |
| WO-1996028445-A1 | NOVEL GLUTAMATE (AMPA/KAINATE) RECEPTOR ANTAGONISTS: N-SUBSTITUTED FUSED AZACYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-09-19 | — | — | WO | claimed |
| US-6197771-B1 | NERVOUS SYSTEM DISORDERS; ANTIISCHEMIC AGENTS; ALZHEIMER'SDISEASE; PARKINSON'S DISEASE; HUNTINGTON'S DISEASE | WARNER-LAMBERT COMPANY | 2001-03-06 | — | — | US | disclosed |
| US-6057313-A | TREATING CENTRAL NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| WO-1996028445-A1 | NOVEL GLUTAMATE (AMPA/KAINATE) RECEPTOR ANTAGONISTS: N-SUBSTITUTED FUSED AZACYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-09-19 | — | — | WO | disclosed |