Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7983995

CCN(C(=O)c1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1)c1ccccc1.O=C(O)C(F)(F)F

nearest known ligand 0.69

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.69
FNTB P49356 20/20 0.69
PGGT1B P53609 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3498702 0.95 FNTA (0.75) FNTAFNTBPGGT1B
SCHEMBL3501180 0.85 FNTA (0.70) FNTAFNTBPGGT1B
SCHEMBL3502217 0.81 FNTA (0.75) FNTAFNTBPGGT1B
SCHEMBL3501138 0.81 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7984077 0.78 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3501017 0.78 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3499546 0.78 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3501308 0.78 FNTA (1.00) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7987638 0.77 FNTA (0.98) FNTAFNTBPGGT1B
SCHEMBL3501034 0.77 FNTA (0.82) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6297239-B1 Inhibitors of prenyl-protein transferase MERCK & CO., INC. 2001-10-02 US disclosed