Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223653 | 0.89 | LCK (0.56) | LCKBTKPGK1LYN | |
| SCHEMBL31136593 | 0.82 | LCK (0.42) | LCKBTKLYN | |
| SCHEMBL31137515 | 0.76 | BTK (0.42) | LCKBTKLYN | |
| SCHEMBL31136256 | 0.76 | BTK (0.36) | LCKBTKLYN | |
| SCHEMBL7969599 | 0.75 | LCK (0.58) | LCKBTK | |
| SCHEMBL31040754 | 0.73 | LCK (0.55) | LCKBTKLYN | |
| SCHEMBL3497163 | 0.73 | LCK (0.55) | LCKBTK | |
| SCHEMBL7969568 | 0.71 | LCK (0.69) | LCK | |
| SCHEMBL7983680 | 0.70 | LCK (0.63) | LCK | |
| SCHEMBL7982977 | 0.70 | LCK (0.61) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |