Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563729 | 1.00 | MDM4 (0.52) | MDM4TSHRMDM2KMT2ANPSR1 | |
| SCHEMBL29400330 | 1.00 | MDM4 (0.52) | MDM4TSHRMDM2KMT2ANPSR1 | |
| SCHEMBL30057042 | 1.00 | MDM4 (0.52) | MDM4TSHRMDM2KMT2ANPSR1 | |
| SCHEMBL21838224 | 1.00 | MDM4 (0.52) | MDM4TSHRMDM2KMT2ANPSR1 | |
| SCHEMBL13743302 | 0.92 | ATM (0.53) | MDM4TP53CASP3 | |
| SCHEMBL29401932 | 0.92 | ATM (0.53) | MDM4TP53CASP3 | |
| SCHEMBL12531899 | 0.92 | ATM (0.53) | MDM4TP53CASP3 | |
| SCHEMBL2977877 | 0.92 | ATM (0.53) | MDM4TP53CASP3 | |
| SCHEMBL12062867 | 0.92 | TSHR (0.54) | MDM4TSHRMDM2KMT2ANPSR1 | |
| SCHEMBL13437618 | 0.92 | TSHR (0.54) | MDM4TSHRMDM2KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212020-B1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | SELLERGREN BOERJE (SE) | 2018-07-04 | — | — | EP | disclosed |
| US-9329186-B2 | Imprinted polymers with affinity for phosphorylated peptides and proteins | MIP TECHNOLOGIES AB (SE) | 2016-05-03 | — | — | US | disclosed |
| US-9329186-B2 | Imprinted polymers with affinity for phosphorylated peptides and proteins | MIP TECHNOLOGIES AB (SE) | 2016-05-03 | — | — | US | disclosed |
| EP-2776409-B1 | MACROCYCLIC COMPOUNDS FOR INHIBITION OF INHIBITORS OF APOPTOSIS | ENSEMBLE THERAPEUTICS CORP (US) | 2016-02-03 | — | — | EP | disclosed |
| WO-2013071035-A1 | MACROCYCLIC COMPOUNDS FOR INHIBITION OF INHIBITORS OF APOPTOSIS | ENSEMBLE THERAPEUTICS (US) | 2013-05-16 | — | — | WO | disclosed |
| US-20110015373-A1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | MIP TECHNOLOGIES AB (SE) | 2011-01-20 | — | — | US | disclosed |
| US-20110015373-A1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | MIP TECHNOLOGIES AB (SE) | 2011-01-20 | — | — | US | disclosed |
| US-7595399-B2 | Tyrosine derivatives | GENENTECH, INC. (US) | 2009-09-29 | — | — | US | disclosed |
| WO-2009064245-A1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | MIP TECHNOLOGIES AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015373-A1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | PHAX, ACP1, CHAMP1 | MDM4 566/4885TSHR 3439/4885MDM2 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.