Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219387 | 0.79 | TSHR (0.53) | TSHRGABRA1GABRB2POLBHTR1A | |
| SCHEMBL6534996 | 0.79 | TSHR (0.46) | TSHRGABRA1GABRB2POLBHTR1A | |
| SCHEMBL6535416 | 0.77 | TSHR (0.65) | TSHRGABRA1GABRB2POLB | |
| SCHEMBL6534963 | 0.76 | TSHR (0.50) | TSHRGABRA1GABRB2POLB | |
| SCHEMBL6534897 | 0.75 | TSHR (0.48) | TSHRGABRA1GABRB2POLBPPARG | |
| SCHEMBL6535244 | 0.73 | TSHR (0.47) | TSHRGABRA1GABRB2PPARG | |
| SCHEMBL6535290 | 0.73 | TSHR (0.47) | TSHRGABRA1GABRB2PPARG | |
| SCHEMBL6534845 | 0.73 | TSHR (0.47) | TSHRGABRA1GABRB2PPARG | |
| SCHEMBL28641283 | 0.73 | TSHR (0.47) | TSHRGABRA1GABRB2PPARG | |
| Bromide SCHEMBL11703211 | 0.72 | TSHR (0.46) | TSHRGABRA1GABRB2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284918-B1 | ENZYME INHIBITORS | VANDERBILT UNIVERSITY | 2001-09-04 | — | — | US | disclosed |