SCHEMBL7984787

SCHEMBL7984787

N#Cc1ccc(Cn2ccnc2)cc1Oc1cccc(Cl)c1Cl

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.84
FNTB P49356 20/20 0.84
PGGT1B P53609 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3499584 0.91 FNTA (1.00) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7983701 0.90 FNTA (0.98) FNTAFNTBPGGT1B
SCHEMBL3501124 0.84 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3501063 0.83 FNTA (0.74) FNTAFNTBPGGT1B
SCHEMBL3501696 0.83 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3501355 0.83 FNTA (0.76) FNTAFNTBPGGT1B
SCHEMBL3504204 0.83 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3500917 0.83 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3504221 0.83 FNTA (0.80) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7984197 0.82 FNTA (0.98) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6297239-B1 Inhibitors of prenyl-protein transferase MERCK & CO., INC. 2001-10-02 US disclosed