Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | PARN | O95453 | 1/20 | 0.37 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985354 | 0.99 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KMT2AHPGDCYP19A1 | |
| SCHEMBL7974103 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL7974024 | 0.77 | HPGD (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL7975267 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL7975252 | 0.74 | HPGD (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL7988099 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL7985343 | 0.74 | GAA (0.44) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL7985301 | 0.74 | KMT2A (0.57) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL7985404 | 0.73 | HPGD (0.49) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL5464971 | 0.73 | PDE4A (0.52) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |