SCHEMBL7985932

SCHEMBL7985932

Clc1coc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769272 0.69
SCHEMBL6824970 0.69
SCHEMBL5156537 0.69
SCHEMBL9769267 0.69
SCHEMBL19501380 0.65
SCHEMBL7992709 0.65
SCHEMBL12869008 0.64
SCHEMBL29956178 0.64
SCHEMBL826851 0.64
SCHEMBL9769040 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496318-A Heterocyclic derivative, composition and pharmaceutical application thereof 四川海思科制药有限公司 2023-07-28 CN disclosed
CN-116217593-A Octahydropyrrolo [3,4-c ] pyrrole methyl ketone derivative and application thereof 江苏恩华药业股份有限公司 2023-06-06 CN disclosed
CN-107531725-B IRAK4 inhibitor and application thereof 北京韩美药品有限公司 2021-03-19 CN disclosed
CN-110396095-A Double aromatic ring derivative egf inhibitors of a kind of Furanopyrimidines and preparation method thereof and purposes YAOYA TECH SHANGHAI CO LTD 2019-11-01 CN disclosed
CN-109071567-A Anti influenza small molecule compound and its preparation method and application 四川大学 2018-12-21 CN disclosed
CN-106083887-B Inhibit the compound of BTK and/or JAK3 kinase activity 北京韩美药品有限公司 2018-11-20 CN disclosed
CN-108586471-A Furans simultaneously [3,2-d] miazines HIV-1 inhibitor and the preparation method and application thereof 山东大学 2018-09-28 CN disclosed
CN-108467369-A BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS 诺华股份有限公司 2018-08-31 CN disclosed
CN-108349910-A glucose uptake inhibitor 卡德门企业有限公司 2018-07-31 CN disclosed
CN-106065017-B Inhibit the compound of BTK and/or JAK3 kinase activities 北京韩美药品有限公司 2018-06-01 CN disclosed
CN-101675053-A Phosphoinositide 3-kinase inhibitor compounds and methods of use GENENTECH INC 2010-03-17 CN disclosed
CN-101600720-A Phosphoinositide 3-kinase inhibitor compounds and using method HOFFMANN LA ROCHE (CH) 2009-12-09 CN disclosed
CN-101511840-A Phosphoinositide 3-kinase inhibitor compounds and methods of use thereof GENENTECH INC (US) 2009-08-19 CN disclosed
CN-101479274-A Pharmaceutical compounds HOFFMANN LA ROCHE (CH) 2009-07-08 CN disclosed
US-6287550-B1 MIXTURES THE PROCTER & GAMBLE COMPANY 2001-09-11 US disclosed
EP-0946209-A2 ABSORBENT ARTICLES WITH ODOR CONTROL SYSTEM THE PROCTER & GAMBLE COMPANY (US) 1999-10-06 EP disclosed
EP-0946808-A2 ANIMAL CARE SYSTEM AND LITTER WITH REDUCED MALODOR IMPRESSION THE PROCTER & GAMBLE COMPANY (US) 1999-10-06 EP disclosed
WO-1998026808-A2 ABSORBENT ARTICLES WITH ODOR CONTROL SYSTEM THE PROCTER & GAMBLE COMPANY (US) 1998-06-25 WO disclosed
WO-1998027261-A2 ANIMAL CARE SYSTEM AND LITTER WITH REDUCED MALODOR IMPRESSION THE PROCTER & GAMBLE COMPANY (US) 1998-06-25 WO disclosed
WO-1996040856-A1 TOILET BOWL CLEANERS CONTAINING UREASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1996-12-19 WO disclosed