Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.72 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.52 |
| ▸ | TNKS | O95271 | 2/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31116604 | 0.89 | GRM5 (0.70) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL2241357 | 0.86 | GRM5 (0.77) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL2246381 | 0.83 | GRM5 (0.82) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL16394406 | 0.83 | GRM5 (0.88) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL12517648 | 0.83 | GRM5 (0.63) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL6499068 | 0.82 | GRM5 (0.66) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL9965813 | 0.82 | GRM5 (0.66) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL22449377 | 0.82 | GRM5 (0.80) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL2590689 | 0.82 | GRM5 (0.80) | GRM5SMYD3KDM4EKMT2AGAA | |
| SCHEMBL29580741 | 0.82 | GRM5 (0.66) | GRM5SMYD3KDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191146-B1 | BACTERICIDES, FUNGICIDES, VIRICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-02-20 | — | — | US | claimed |
| EP-0866700-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-04-07 | — | — | EP | claimed |
| EP-0866700-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-30 | — | — | EP | claimed |
| WO-1997017958-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | claimed |
| US-6191146-B1 | BACTERICIDES, FUNGICIDES, VIRICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-02-20 | — | — | US | disclosed |
| EP-0866700-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0866700-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997017958-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |