Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961504 | 0.81 | CRBN (0.32) | CRBN | |
| SCHEMBL444955 | 0.69 | — | — | |
| SCHEMBL208133 | 0.68 | — | — | |
| SCHEMBL18397956 | 0.68 | — | — | |
| SCHEMBL33371399 | 0.67 | CRBN (0.33) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL248663 | 0.64 | DDB1 (0.33) | CRBNDDB1 | |
| SCHEMBL6196078 | 0.61 | CRBN (0.35) | CRBN | |
| SCHEMBL10620948 | 0.60 | CRBN (0.42) | CRBNDDB1 | |
| SCHEMBL16397715 | 0.60 | — | — | |
| SCHEMBL2138420 | 0.60 | CRBN (0.34) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288824-A | Tetrahydropyridopyridone derivative as well as preparation method and application thereof | UNIV SHANGHAI | 2013-09-11 | — | — | CN | disclosed |
| US-6265406-B1 | VIRICIDES | DUPONT PHARMACEUTICALS COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6090821-A | ENZYME INHIBITORS; VIRICIDES | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 2000-07-18 | — | — | US | disclosed |