Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7974228 | 0.99 | GAA (0.50) | GAATP53RXFP1YTHDC1HPGD | |
| SCHEMBL7984510 | 0.89 | GAA (0.53) | GAATP53RXFP1YTHDC1HPGD | |
| SCHEMBL7984130 | 0.87 | GAA (0.52) | GAATP53RXFP1YTHDC1HPGD | |
| SCHEMBL7988361 | 0.87 | HPGD (0.47) | TP53HPGDALDH1A1SMN1; SMN2HCAR2 | |
| SCHEMBL7985271 | 0.86 | GAA (0.51) | GAATP53RXFP1HPGDALDH1A1 | |
| SCHEMBL7987671 | 0.86 | SMN1; SMN2 (0.48) | GAAYTHDC1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7989507 | 0.86 | HPGD (0.46) | GAAYTHDC1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7984363 | 0.85 | SMN1; SMN2 (0.59) | GAARXFP1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7986366 | 0.85 | TP53 (0.51) | GAATP53RXFP1YTHDC1ROCK1 | |
| Hydrochloric Acid SCHEMBL7987800 | 0.85 | HPGD (0.48) | GAAYTHDC1HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |