Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986534 | 1.00 | F2RL1 (0.35) | F2RL1DGAT1MAPT | |
| SCHEMBL13871296 | 0.79 | F2RL1 (0.35) | F2RL1DGAT1MAPT | |
| SCHEMBL13871297 | 0.76 | F2RL1 (0.33) | F2RL1DGAT1MAPT | |
| SCHEMBL18338609 | 0.73 | TLR7 (0.33) | F2RL1 | |
| SCHEMBL18338490 | 0.72 | F2RL1 (0.34) | F2RL1 | |
| SCHEMBL25419187 | 0.71 | F2RL1 (0.33) | F2RL1DGAT1MAPT | |
| SCHEMBL15438132 | 0.70 | ATR (0.36) | F2RL1DGAT1MAPT | |
| SCHEMBL18338379 | 0.69 | USP2 (0.31) | F2RL1 | |
| SCHEMBL19332634 | 0.69 | KDM4E (0.42) | F2RL1DGAT1 | |
| SCHEMBL4555226 | 0.69 | F2RL1 (0.38) | F2RL1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |