Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.51 |
| ▸ | MTOR | P42345 | 10/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.49 |
| ▸ | PI4KA | P42356 | 6/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790017 | 0.86 | PIK3CG (0.63) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL806799 | 0.85 | PIK3CA (0.62) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL30333043 | 0.79 | PIK3CA (0.68) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL10274850 | 0.78 | PIK3CG (0.68) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL25389572 | 0.78 | PIK3CA (0.58) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL25389354 | 0.78 | PIK3CA (0.59) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL31185588 | 0.78 | PIK3CA (0.58) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL789777 | 0.78 | PIK3CG (0.66) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL31185592 | 0.78 | PIK3CA (0.59) | PIK3CAMTORPIK3CGPI4KAPIK3CD | |
| SCHEMBL25387808 | 0.78 | PIK3CA (0.59) | PIK3CAMTORPIK3CGPI4KAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |