Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16466899 | 0.87 | SCN8A (0.54) | SCN8ACA12CA2CA9KDM4E | |
| SCHEMBL25590510 | 0.84 | SCN8A (0.59) | SCN8ACA12CA2CA9CHRM2 | |
| SCHEMBL7077084 | 0.83 | SCN8A (0.60) | SCN8ACA12CA2CA9CHRM2 | |
| SCHEMBL13975078 | 0.81 | SCN8A (0.62) | SCN8ACA12CA2CA9CHRM2 | |
| SCHEMBL13436118 | 0.79 | SCN8A (0.54) | SCN8AKDM4ETSHRALDH1A1HTT | |
| SCHEMBL17274380 | 0.78 | HDAC1 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL21674183 | 0.77 | SCN8A (0.57) | SCN8AKDM4EALDH1A1HTTTDP1 | |
| SCHEMBL16269037 | 0.77 | SCN8A (0.54) | SCN8ACA12CA2KDM4EALDH1A1 | |
| SCHEMBL10925708 | 0.76 | CHRM2 (0.80) | CA12CA2CA9CHRM2TSHR | |
| SCHEMBL17400756 | 0.76 | CA12 (0.56) | CA12CA2CA9CHRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |