Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.57 |
| ▸ | HTR3A | P46098 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | KHK | P50053 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669331 | 0.88 | BCHE (0.51) | SLC6A4SLC6A2SLC6A3HTR3AHTR2A | |
| SCHEMBL8669223 | 0.85 | BCHE (0.59) | SLC6A4SLC6A2SLC6A3HTR3AHTR2A | |
| SCHEMBL1581852 | 0.83 | GBA1 (0.62) | SLC6A4SLC6A2SLC6A3HTR3AHTR2A | |
| Hydrochloric Acid SCHEMBL7403430 | 0.82 | GBA1 (0.61) | SLC6A4SLC6A2SLC6A3HTR3AHTR2A | |
| SCHEMBL2241250 | 0.79 | GBA1 (0.66) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL1532936 | 0.78 | GBA1 (0.63) | SLC6A4 | |
| SCHEMBL12736142 | 0.76 | GBA1 (0.53) | SLC6A4HTR7HRH3KHK | |
| SCHEMBL30186215 | 0.75 | SLC6A2 (0.73) | SLC6A4SLC6A2SLC6A3HTR3AHTR2A | |
| Hydrochloric Acid SCHEMBL1532929 | 0.75 | GBA1 (0.51) | SLC6A4HRH3KHK | |
| SCHEMBL12735989 | 0.74 | TAAR1 (0.47) | SLC6A4HRH3KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |