Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985922 | 0.87 | CA1 (0.47) | PRMT5WDR77CA1CA2CA7 | |
| SCHEMBL5742123 | 0.87 | CA1 (0.56) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL7511915 | 0.81 | CA1 (0.50) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL7989918 | 0.81 | CA1 (0.50) | PRMT5WDR77CA1CA2CA7 | |
| SCHEMBL7515243 | 0.81 | PRMT5 (0.42) | PRMT5WDR77CA1CA2CA7 | |
| SCHEMBL7986919 | 0.80 | CA1 (0.49) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL7988903 | 0.80 | CA1 (0.49) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL7987465 | 0.78 | CA1 (0.47) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL7504436 | 0.78 | SMN1; SMN2 (0.48) | PRMT5WDR77CA1CA2CA7 | |
| SCHEMBL6549684 | 0.78 | CA1 (0.47) | CA1CA2CA7CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |