Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618268 | 1.00 | CCNA2 (0.37) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL9176156 | 0.85 | CCNA2 (0.44) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL8188002 | 0.83 | CCNA2 (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL29102259 | 0.83 | MEN1 (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL13294275 | 0.82 | CCNA2 (0.34) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL19161112 | 0.81 | HPGD (0.37) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL30940157 | 0.81 | CCNA2 (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL3612332 | 0.80 | GAA (0.40) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL25309750 | 0.78 | CCNA2 (0.34) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL17503328 | 0.78 | EPHX2 (0.36) | CCNA2CDK2CCNA1CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |