Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 17/20 | 0.69 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938414 | 0.93 | MCHR1 (0.61) | CCR3MCHR1TACR1 | |
| SCHEMBL7935503 | 0.91 | CCR3 (0.66) | CCR3TACR1 | |
| SCHEMBL7932661 | 0.87 | CCR3 (0.75) | CCR3MCHR1TACR1 | |
| SCHEMBL7938286 | 0.86 | CCR3 (0.84) | CCR3TACR1 | |
| SCHEMBL7935308 | 0.86 | TACR1 (0.72) | CCR3TACR1 | |
| SCHEMBL7925950 | 0.84 | CCR3 (0.77) | CCR3TACR1 | |
| SCHEMBL7993636 | 0.84 | TACR1 (0.77) | CCR3TACR1 | |
| SCHEMBL7932773 | 0.84 | CCR3 (0.77) | CCR3TACR1 | |
| SCHEMBL7934923 | 0.83 | CCR3 (0.76) | CCR3TACR1 | |
| SCHEMBL7934778 | 0.82 | CCR3 (0.75) | CCR3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |