⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874301 | 0.77 | — | — | |
| SCHEMBL10722626 | 0.72 | — | — | |
| SCHEMBL3259513 | 0.71 | CA1 (0.31) | — | |
| SCHEMBL6918650 | 0.67 | — | — | |
| SCHEMBL11182940 | 0.59 | — | — | |
| SCHEMBL9768004 | 0.58 | — | — | |
| SCHEMBL17756694 | 0.58 | — | — | |
| SCHEMBL257414 | 0.57 | — | — | |
| SCHEMBL2760184 | 0.54 | — | — | |
| SCHEMBL18285261 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262073-B1 | INHIBITING THE ACTION OF A PRO-INFLAMMATORY CYTOKINE | OXIS INTERNATIONAL INC. | 2001-07-17 | — | — | US | disclosed |