Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284959 | 0.81 | KMT2A (0.39) | KMT2ARAB9AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL6283661 | 0.75 | KMT2A (0.37) | KMT2ARAB9AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL6289753 | 0.74 | KMT2A (0.39) | KMT2ARAB9AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL176995 | 0.72 | POLB (0.44) | TSHRKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6290259 | 0.72 | KMT2A (0.36) | KMT2ARAB9AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL8409752 | 0.71 | KMT2A (0.38) | TSHRKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL2637094 | 0.70 | FFAR1 (0.44) | TSHRKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL21244970 | 0.70 | POLB (0.42) | KMT2ARAB9AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL27830382 | 0.70 | KMT2A (0.35) | KMT2ARAB9AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL6289665 | 0.69 | POLB (0.41) | KMT2ARAB9AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284767-B1 | AIDS; MIXTURE WITH ENZYME INHIBITOR | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |