Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31567826 | 1.00 | CRBN (0.60) | CRBNHPGDHRH3SMYD3KDM1A | |
| SCHEMBL13498283 | 0.94 | CRBN (0.57) | CRBNHPGDHRH3KDM1AMAOA | |
| SCHEMBL1781864 | 0.89 | ACKR3 (0.55) | CRBNHRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL28189608 | 0.84 | HDAC4 (0.55) | CRBNHRH3 | |
| SCHEMBL28189609 | 0.84 | HDAC4 (0.55) | CRBNHRH3 | |
| SCHEMBL14454263 | 0.84 | HRH3 (0.49) | CRBNHPGDHRH3SMN1; SMN2MEN1 | |
| SCHEMBL4191547 | 0.83 | HPGD (0.71) | HPGDHRH3SMYD3NPC1RAB9A | |
| SCHEMBL19990874 | 0.82 | CRBN (0.50) | CRBNHRH3NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18115907 | 0.82 | CRBN (0.50) | CRBNHRH3NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3225623 | 0.81 | HPGD (0.55) | CRBNHPGDHRH3KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262736-A | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| EP-2298747-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |