Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986721 | 1.00 | DRD4 (0.47) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| SCHEMBL7986622 | 1.00 | DRD4 (0.47) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| Hydrochloric Acid SCHEMBL7972397 | 0.99 | DRD4 (0.46) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| Hydrochloric Acid SCHEMBL7989815 | 0.99 | DRD4 (0.46) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| Hydrochloric Acid SCHEMBL7972322 | 0.99 | DRD4 (0.46) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| SCHEMBL7971899 | 0.95 | DRD4 (0.52) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| Hydrochloric Acid SCHEMBL7971892 | 0.94 | DRD4 (0.52) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| SCHEMBL7971755 | 0.92 | DRD4 (0.53) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| Hydrochloric Acid SCHEMBL7983770 | 0.92 | DRD4 (0.52) | DRD4SIGMAR1FLT3TYRO3MERTK | |
| SCHEMBL7983507 | 0.91 | DRD4 (0.51) | DRD4SIGMAR1FLT3TYRO3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |