Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788637 | 0.91 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL788800 | 0.80 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL788673 | 0.73 | PIK3CD (0.68) | PIK3CD | |
| SCHEMBL788788 | 0.71 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL788465 | 0.71 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL18923876 | 0.70 | PIK3CD (0.63) | PIK3CD | |
| SCHEMBL682357 | 0.69 | PIK3CD (0.76) | PIK3CD | |
| SCHEMBL788217 | 0.69 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL788238 | 0.69 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL31733002 | 0.68 | SCN9A (0.47) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616442-A1 | INHIBITORS OF PI3K-DELTA AND METHODS OF THEIR USE AND MANUFACTURE | Exelixis, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037204-A1 | INHIBITORS OF PI3K-DELTA AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |