Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001710 | 0.95 | GSK3B (0.43) | PARP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7997301 | 0.95 | GSK3B (0.43) | PARP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8004454 | 0.90 | PARP1 (0.46) | PARP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8004352 | 0.88 | PARP1 (0.49) | PARP1KDM4EALDH1A1HSD17B10GRIN2D | |
| SCHEMBL8004476 | 0.85 | PARP1 (0.43) | PARP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8004628 | 0.85 | PARP1 (0.46) | PARP1KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL8001131 | 0.85 | PARP1 (0.46) | PARP1KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL7998930 | 0.85 | PARP1 (0.46) | PARP1KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL8001410 | 0.85 | PARP1 (0.46) | PARP1KDM4EALDH1A1HSD17B10GRIN2D | |
| SCHEMBL8001244 | 0.85 | PARP1 (0.46) | PARP1KDM4EALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |