Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | HTR1D | P28221 | 5/20 | 0.36 |
| ▸ | HTR1B | P28222 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000822 | 0.95 | PARP1 (0.43) | PARP1TSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8001892 | 0.95 | PARP1 (0.43) | PARP1TSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8001410 | 0.95 | PARP1 (0.46) | PARP1ALDH1A1KDM4ESMN1; SMN2CNR2 | |
| SCHEMBL7988816 | 0.94 | PARP1 (0.47) | PARP1TSHRALDH1A1KDM4ECNR2 | |
| SCHEMBL7988879 | 0.94 | PARP1 (0.47) | PARP1TSHRALDH1A1KDM4ECNR2 | |
| SCHEMBL8001131 | 0.93 | PARP1 (0.46) | PARP1TSHRALDH1A1KDM4ECNR2 | |
| SCHEMBL8004628 | 0.93 | PARP1 (0.46) | PARP1TSHRALDH1A1KDM4ECNR2 | |
| SCHEMBL7998930 | 0.93 | PARP1 (0.46) | PARP1TSHRALDH1A1KDM4ECNR2 | |
| SCHEMBL8001244 | 0.90 | PARP1 (0.46) | PARP1ALDH1A1KDM4ESMN1; SMN2CNR2 | |
| SCHEMBL8004352 | 0.89 | PARP1 (0.49) | PARP1ALDH1A1KDM4ECNR2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |