Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992389 | 0.90 | DPP4 (0.78) | DPP4FAP | |
| SCHEMBL7992099 | 0.86 | DPP4 (0.73) | DPP4FAP | |
| SCHEMBL7992095 | 0.86 | DPP4 (0.73) | DPP4FAP | |
| Trifluoroacetic Acid SCHEMBL7978160 | 0.84 | DPP4 (0.69) | DPP4FAP | |
| SCHEMBL7989090 | 0.83 | DPP4 (0.76) | DPP4 | |
| SCHEMBL7989092 | 0.83 | DPP4 (0.76) | DPP4 | |
| SCHEMBL15827030 | 0.83 | DPP4 (1.00) | DPP4FAP | |
| SCHEMBL14392405 | 0.83 | DPP4 (1.00) | DPP4FAP | |
| SCHEMBL7989871 | 0.83 | DPP4 (0.75) | DPP4FAP | |
| SCHEMBL7989872 | 0.83 | DPP4 (0.75) | DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172081-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS; NON-INSULIN DEPENDENT DIABETES | NOVARTIS AG (CH) | 2001-01-09 | — | — | US | claimed |
| US-6172081-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS; NON-INSULIN DEPENDENT DIABETES | NOVARTIS AG (CH) | 2001-01-09 | — | — | US | disclosed |