Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988768 | 0.88 | MEN1 (0.68) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL4472638 | 0.88 | MEN1 (0.64) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL19227456 | 0.82 | POLB (0.71) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL17537447 | 0.79 | SYK (0.59) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL3426969 | 0.79 | SYK (0.59) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL14577958 | 0.79 | POLB (0.59) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL14578262 | 0.79 | SYK (0.59) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL348153 | 0.78 | MEN1 (0.59) | MEN1KMT2ASYKNPC1POLB | |
| SCHEMBL11530386 | 0.78 | KMT2A (0.61) | MEN1KMT2ANPC1POLBSMN1; SMN2 | |
| SCHEMBL11530097 | 0.78 | KMT2A (0.61) | MEN1KMT2APOLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |