Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CNOT7 | Q9UIV1 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARN | O95453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988857 | 0.93 | CNOT7 (0.43) | HTTCNOT7ADORA2ACYP2A6HTR2A | |
| SCHEMBL7985637 | 0.89 | SMN1; SMN2 (0.43) | CNOT7ALDH1A1ADORA2APKMSMN1; SMN2 | |
| SCHEMBL7985082 | 0.89 | HTT (0.46) | HTTCNOT7ALDH1A1ADORA2APKM | |
| Hydrochloric Acid SCHEMBL7987616 | 0.88 | SMN1; SMN2 (0.42) | CNOT7ALDH1A1ADORA2APKMSMN1; SMN2 | |
| SCHEMBL7974534 | 0.86 | CNOT7 (0.45) | HTTCNOT7ALDH1A1ADORA2APKM | |
| SCHEMBL7984709 | 0.83 | CNOT7 (0.42) | HTTCNOT7ALDH1A1ADORA2AKMT2A | |
| Hydrochloric Acid SCHEMBL7984350 | 0.82 | CNOT7 (0.41) | HTTCNOT7ALDH1A1ADORA2AKMT2A | |
| SCHEMBL7987235 | 0.81 | TSHR (0.46) | HTTCNOT7ALDH1A1ADORA2AKMT2A | |
| SCHEMBL7985319 | 0.81 | SMN1; SMN2 (0.42) | CNOT7ALDH1A1ADORA2APKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7987745 | 0.81 | SMN1; SMN2 (0.41) | CNOT7ALDH1A1ADORA2APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |