Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31554343 | 0.86 | KCNH2 (0.47) | KCNH2ALDH1A1LMNACYP3A4HRH3 | |
| SCHEMBL675808 | 0.86 | KCNH2 (0.47) | KCNH2ALDH1A1LMNACYP3A4HRH3 | |
| SCHEMBL2697514 | 0.86 | KCNH2 (0.47) | KCNH2ALDH1A1LMNACYP3A4HRH3 | |
| SCHEMBL360634 | 0.86 | KCNH2 (0.47) | KCNH2ALDH1A1LMNACYP3A4HRH3 | |
| SCHEMBL674217 | 0.86 | KCNH2 (0.47) | KCNH2ALDH1A1LMNACYP3A4HRH3 | |
| SCHEMBL2697904 | 0.86 | KCNH2 (0.47) | KCNH2ALDH1A1LMNACYP3A4HRH3 | |
| SCHEMBL7991392 | 0.85 | HRH3 (0.33) | USP2LMNASMN1; SMN2HRH3 | |
| Bromide SCHEMBL38663385 | 0.84 | KCNH2 (0.46) | KCNH2ALDH1A1LMNACYP3A4HRH3 | |
| SCHEMBL4376138 | 0.79 | HRH3 (0.32) | CDK1CCNB1HRH3CCNA2CDK2 | |
| SCHEMBL4383571 | 0.79 | HRH3 (0.52) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |