Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800866 | 0.95 | KDM4E (0.70) | KDM4EATMGLASMN1; SMN2TSHR | |
| SCHEMBL5688791 | 0.93 | KDM4E (0.66) | KDM4EATMGLASMN1; SMN2TSHR | |
| SCHEMBL5690757 | 0.91 | GLA (0.64) | KDM4EATMGLASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL11691494 | 0.89 | GLA (0.67) | KDM4EATMGLASMN1; SMN2TSHR | |
| SCHEMBL12071540 | 0.89 | KDM4E (0.70) | KDM4EATMGLASMN1; SMN2TSHR | |
| SCHEMBL9827576 | 0.88 | CSNK2A1 (0.54) | KDM4EATMSIGMAR1 | |
| SCHEMBL8000030 | 0.87 | GLA (0.72) | KDM4EATMGLASMN1; SMN2TSHR | |
| SCHEMBL7366948 | 0.87 | KDM4E (0.66) | KDM4EATMGLASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL9828846 | 0.86 | CSNK2A1 (0.55) | GLASMN1; SMN2SIGMAR1 | |
| SCHEMBL2742569 | 0.84 | KDM4E (0.72) | KDM4EATMGLASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |