Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439454 | 0.81 | SLC1A3 (0.43) | IDO1KDM4EKMT2AALDH1A1 | |
| SCHEMBL1883601 | 0.81 | SLC1A3 (0.43) | IDO1KDM4EKMT2AALDH1A1 | |
| SCHEMBL16599792 | 0.79 | IDO1 (0.48) | IDO1APPRXRARXRBMAOB | |
| SCHEMBL7450464 | 0.77 | MAOB (0.41) | IDO1MAOB | |
| SCHEMBL7987752 | 0.77 | CA1 (0.47) | KMT2A | |
| SCHEMBL29752790 | 0.77 | SLC1A3 (0.43) | IDO1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28088941 | 0.75 | SLC1A3 (0.39) | IDO1KMT2A | |
| SCHEMBL7989863 | 0.71 | IDO1 (0.36) | IDO1MAOBKMT2AALDH1A1HPGD | |
| SCHEMBL7792930 | 0.70 | IDO1 (0.44) | IDO1RXRARXRBMAOBKDM4E | |
| SCHEMBL19930587 | 0.70 | KMT2A (0.41) | IDO1APPRXRARXRBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329526-B1 | Cycloalkyl substituted imidazoles | SMITHKLINE BEECHAM CORPORATION | 2001-12-11 | — | — | US | claimed |
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |