Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938523 | 0.93 | TACR1 (0.78) | TACR1 | |
| SCHEMBL7925954 | 0.93 | TACR1 (0.84) | TACR1 | |
| SCHEMBL9055378 | 0.87 | TACR1 (1.00) | TACR1 | |
| SCHEMBL9056368 | 0.87 | TACR1 (0.80) | TACR1 | |
| SCHEMBL7934766 | 0.87 | TACR1 (0.84) | TACR1 | |
| SCHEMBL7938447 | 0.86 | TACR1 (0.80) | TACR1 | |
| SCHEMBL7935238 | 0.86 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7935432 | 0.85 | TACR1 (1.00) | TACR1 | |
| SCHEMBL9055256 | 0.85 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7936465 | 0.85 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |
| US-5708006-A | ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-01-13 | — | — | US | disclosed |