Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PARN | O95453 | 1/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987608 | 0.97 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL7989405 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL7985314 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL7975251 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7988836 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| Hydrochloric Acid SCHEMBL7987741 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| Hydrochloric Acid SCHEMBL7975095 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL7985634 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| SCHEMBL7987702 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 | |
| Hydrochloric Acid SCHEMBL7987615 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDKMT2AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |