Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.50 |
| ▸ | F2 | P00734 | 9/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603846 | 0.98 | ESR1 (0.52) | ESR1ESR2F2ITGA4 | |
| Oxalic Acid SCHEMBL7971945 | 0.92 | F2 (0.50) | ESR1ESR2F2ITGA4 | |
| Oxalic Acid SCHEMBL6609726 | 0.91 | ESR1 (0.53) | ESR1ESR2F2ITGA4 | |
| SCHEMBL7983860 | 0.91 | F2 (0.53) | ESR1ESR2F2ITGA4 | |
| Oxalic Acid SCHEMBL6611102 | 0.90 | ESR1 (0.49) | ESR1ESR2F2ITGA4 | |
| Oxalic Acid SCHEMBL7981792 | 0.89 | F2 (0.58) | ESR1ESR2F2ITGA4 | |
| SCHEMBL7985788 | 0.89 | ESR1 (0.52) | ESR1ESR2F2ITGA4 | |
| SCHEMBL7972400 | 0.89 | ESR1 (0.59) | ESR1ESR2F2ITGA4 | |
| SCHEMBL6604504 | 0.89 | F2 (0.58) | ESR1ESR2F2ITGA4 | |
| SCHEMBL6606766 | 0.89 | ESR1 (0.55) | ESR1ESR2F2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |