Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630724 | 0.94 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL4630639 | 0.91 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6152582 | 0.90 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631401 | 0.87 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7228902 | 0.85 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4632375 | 0.84 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL4631835 | 0.84 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL4631405 | 0.82 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4631898 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631800 | 0.82 | EDNRA (0.78) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331637-B1 | N-Alkyl, N-Alkenyl, N-Alkynyl, N-Aryl and N-fused bicyclo or tricyclo thienyl-, furyl-,and Pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION | 2001-12-18 | — | — | US | disclosed |