Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663316 | 0.85 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7080378 | 0.81 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL4631366 | 0.78 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL3634612 | 0.78 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7224061 | 0.76 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL2842500 | 0.76 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631365 | 0.75 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631879 | 0.75 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL7224859 | 0.74 | EDNRB (0.68) | EDNRAEDNRB | |
| SCHEMBL9063022 | 0.74 | EDNRB (0.68) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331637-B1 | N-Alkyl, N-Alkenyl, N-Alkynyl, N-Aryl and N-fused bicyclo or tricyclo thienyl-, furyl-,and Pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION | 2001-12-18 | — | — | US | disclosed |