Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.64 |
| ▸ | KDM4D | Q6B0I6 | 6/20 | 0.64 |
| ▸ | KDM6B | O15054 | 9/20 | 0.59 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KDM4A | O75164 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934772 | 0.86 | IRAK4 (0.49) | KDM4CKDM4DKDM6BEGLN3KDM5A | |
| SCHEMBL4439968 | 0.82 | KDM4C (0.69) | KDM4CKDM4DKDM6BEGLN3KDM5A | |
| SCHEMBL20982055 | 0.79 | KDM4C (0.70) | KDM4CKDM4DKDM6BEGLN3KDM5B | |
| SCHEMBL4932602 | 0.79 | KDM4C (0.56) | KDM4CKDM4DKDM6BEGLN3KDM5A | |
| SCHEMBL13789509 | 0.78 | KDM4C (0.67) | KDM4CKDM4DKDM6BEGLN3KDM5A | |
| SCHEMBL15295159 | 0.78 | KDM4C (1.00) | KDM4CKDM4DKDM6BEGLN3KDM5A | |
| SCHEMBL12830011 | 0.78 | KDM4C (0.68) | KDM4CKDM4DKDM6BEGLN3KDM5B | |
| SCHEMBL31574278 | 0.78 | KDM4C (1.00) | KDM4CKDM4DKDM6BEGLN3KDM5A | |
| SCHEMBL16703135 | 0.77 | KDM4C (0.58) | KDM4CKDM4DKDM6BEGLN3KDM5A | |
| SCHEMBL23796861 | 0.76 | KDM4C (0.64) | KDM4CKDM4DKDM6BEGLN3KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062199-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2000-12-27 | — | — | EP | claimed |
| WO-1999046236-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | claimed |
| US-6225329-B1 | USEFUL IN THE TREATMENT OF TYPE I DIABETES, TYPE II DIABETES, IMPAIRED GLUCOSE TOLERANCE, INSULIN AUTOIMMUNITY DISEASES WITH DYSFUNCTIONS OF THE COAGULATION SYSTEM, ALLERGIC DISEASES | NOVO NORDISK A/S (DK) | 2001-05-01 | — | — | US | disclosed |
| EP-1062199-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046236-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | disclosed |