Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 7/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066249 | 0.82 | MAOB (0.64) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL86452 | 0.82 | MAOB (0.54) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL29982629 | 0.82 | MAOB (0.54) | MAOBMAOAGRM5PBRM1LMNA | |
| SCHEMBL67609 | 0.82 | MAOB (0.54) | MAOBMAOAGRM5PBRM1LMNA | |
| SCHEMBL29825555 | 0.82 | MAOB (0.64) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL27942636 | 0.79 | MAOB (0.60) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| Formaldehyde SCHEMBL28160192 | 0.79 | MAOB (0.51) | MAOBMAOAGRM5PBRM1LMNA | |
| Formaldehyde SCHEMBL28233549 | 0.79 | MAOB (0.60) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL32670081 | 0.77 | MAOB (0.47) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL32670189 | 0.77 | MAOB (0.47) | MAOBMAOAGRM5NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211385-B1 | STARTING FROM THIOCHROMAN-4-ONE COMPOUND | ALLERGAN SALES, INC. | 2001-04-03 | — | — | US | disclosed |
| US-6043381-A | Process for preparing substituted benzo[1,2-g]-chrom-3-ene, benzo[1,2-g]-thiochrom-3-ene and benzo[1,2-g]-1,2-dihydroquinoline derivatives | ALLERGAN SALES, INC. (US) | 2000-03-28 | — | — | US | disclosed |