⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226 | 1.00 | — | — | |
| SCHEMBL7402873 | 1.00 | — | — | |
| SCHEMBL1525314 | 0.95 | — | — | |
| SCHEMBL14352041 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL28541874 | 0.95 | — | — | |
| Ethane SCHEMBL7906465 | 0.95 | — | — | |
| SCHEMBL28583701 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL16280747 | 0.76 | — | — | |
| SCHEMBL7740452 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL302698 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134617-A1 | AMINODIHYDROTHIAZINE DERIVATIVES AS BACE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 2009-11-05 | — | — | WO | disclosed |
| US-7410956-B2 | Caspase inhibitor prodrugs | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-08-12 | — | — | US | disclosed |
| US-20080157144-A1 | CMOS IMAGE SENSOR AND FABRICATING METHOD THEREOF | DONGBU HITEK CO., LTD. (KR) | 2008-07-03 | — | — | US | disclosed |
| US-5166167-A | Fungicides | ROUSSEL UCLAF (FR) | 1992-11-24 | — | — | US | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |
| EP-0508901-A2 | Alpha-methylene-4-[(phenoxy)methyl)]5-thiazolacetic acid derivatives, process for their preparation, intermediates in this process, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-14 | — | — | EP | disclosed |