Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548036 | 0.88 | ESR2 (0.48) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL12393136 | 0.88 | ESR2 (0.52) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL2921637 | 0.88 | ESR2 (0.52) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL6198277 | 0.87 | NR1H2 (0.53) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL8556789 | 0.86 | ESR2 (0.50) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL7975391 | 0.85 | POLB (0.50) | POLBHDAC6MAPK1MAPTKDM4E | |
| SCHEMBL19539155 | 0.85 | ESR2 (0.49) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL3441375 | 0.84 | ESR2 (0.49) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL12340040 | 0.83 | ESR2 (0.47) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL5548939 | 0.83 | ESR2 (0.47) | ESR2NR1H2BRD4CREBBPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |