Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 17/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783779 | 0.91 | CHRM2 (0.58) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL10279245 | 0.90 | CHRM2 (0.61) | CHRM2CHRM3ADRB2SLC2A1 | |
| SCHEMBL10279587 | 0.90 | CHRM2 (0.58) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL783829 | 0.89 | CHRM2 (0.59) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL10279630 | 0.89 | CHRM2 (0.61) | CHRM2CHRM3ADRB2SLC2A1 | |
| SCHEMBL4421627 | 0.88 | CHRM3 (0.57) | CHRM2CHRM3ADRB2 | |
| SCHEMBL643545 | 0.86 | CHRM2 (0.70) | CHRM2CHRM3ADRB2 | |
| SCHEMBL783794 | 0.86 | CHRM2 (0.53) | CHRM2CHRM3SLC2A1 | |
| Hydrochloric Acid SCHEMBL381044 | 0.86 | CHRM2 (0.55) | CHRM2CHRM3ADRB2 | |
| SCHEMBL645125 | 0.86 | CHRM2 (0.73) | CHRM2CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | CHRM2 2/4885CHRM3 1/4885ADRB2 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.