Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 9/20 | 1.00 |
| ▸ | SELE | P16581 | 2/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993313 | 1.00 | SELP (1.00) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL7993320 | 1.00 | SELP (1.00) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL7996989 | 1.00 | SELP (1.00) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL7996982 | 1.00 | SELP (1.00) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL7996996 | 1.00 | SELP (1.00) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL7995557 | 0.92 | SELP (0.85) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL7995562 | 0.92 | SELP (0.85) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL8181836 | 0.85 | SELP (0.74) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL8267398 | 0.83 | SELP (0.71) | SELPSELEPTPN1EGFRAPP | |
| SCHEMBL8267390 | 0.83 | SELP (0.71) | SELPSELEPTPN1EGFRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2000033836-A1 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |