Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986305 | 0.91 | MAPK1 (0.56) | ECE1MAPK1SMN1; SMN2 | |
| SCHEMBL7990023 | 0.89 | MAPK1 (0.56) | ECE1MAPK1SMN1; SMN2LTA4HACE | |
| Hydrochloric Acid SCHEMBL7975805 | 0.87 | ECE1 (0.53) | ECE1MAPK1SMN1; SMN2ACE | |
| SCHEMBL7987497 | 0.86 | MAPK1 (0.58) | ECE1MAPK1SMN1; SMN2ACE | |
| SCHEMBL8809326 | 0.86 | SMN1; SMN2 (0.53) | ECE1MAPK1SMN1; SMN2ACE | |
| SCHEMBL7989694 | 0.85 | MAPK1 (0.57) | ECE1MAPK1SMN1; SMN2ACE | |
| SCHEMBL7987457 | 0.85 | MAPK1 (0.57) | ECE1MAPK1SMN1; SMN2ACE | |
| SCHEMBL7988097 | 0.85 | ACE (0.59) | ECE1MAPK1SMN1; SMN2ACE | |
| SCHEMBL7987643 | 0.85 | MAPK1 (0.51) | ECE1MAPK1SMN1; SMN2ACE | |
| SCHEMBL7989691 | 0.84 | ECE1 (0.60) | ECE1MAPK1SMN1; SMN2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |