Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | NNMT | P40261 | 3/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29524193 | 0.88 | NAPRT (0.67) | SMN1; SMN2TDP1NAPRTNNMTL3MBTL1 | |
| SCHEMBL388168 | 0.88 | NAPRT (0.67) | SMN1; SMN2TDP1NAPRTNNMTL3MBTL1 | |
| Pyridine SCHEMBL28131297 | 0.87 | NAPRT (0.58) | SMN1; SMN2GAATDP1NAPRTGRM5 | |
| Hydrochloric Acid SCHEMBL3346497 | 0.86 | NAPRT (0.64) | SMN1; SMN2TDP1NAPRTNNMTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5013500 | 0.86 | NAPRT (0.64) | SMN1; SMN2TDP1NAPRTNNMTL3MBTL1 | |
| Niacinamide SCHEMBL15662857 | 0.82 | F7 (0.71) | SMN1; SMN2GAATDP1NAPRTNNMT | |
| 2-Chloropyridine SCHEMBL28789823 | 0.80 | TDP1 (0.76) | SMN1; SMN2GAATDP1NAPRTGRM5 | |
| SCHEMBL11582144 | 0.79 | NAPRT (0.56) | SMN1; SMN2TDP1NAPRTNNMTL3MBTL1 | |
| SCHEMBL5008264 | 0.78 | NAPRT (0.55) | SMN1; SMN2GAATDP1NAPRTNNMT | |
| SCHEMBL5013439 | 0.78 | NAPRT (0.55) | SMN1; SMN2GAATDP1NAPRTNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036390-A1 | INDAZOLYLOXY PROPANOLAMINES FOR IMPROVING LIVESTOCK PRODUCTION | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |