Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 17/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10279761 | 0.90 | CHRM2 (0.52) | CHRM2CHRM3 | |
| SCHEMBL783694 | 0.90 | CHRM3 (0.54) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL783846 | 0.88 | CHRM3 (0.54) | CHRM2CHRM3 | |
| SCHEMBL644586 | 0.86 | CHRM2 (0.61) | CHRM2CHRM3 | |
| SCHEMBL381334 | 0.84 | CHRM2 (0.59) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL2456805 | 0.84 | CHRM2 (0.62) | CHRM2CHRM3 | |
| SCHEMBL10279635 | 0.83 | CHRM3 (0.56) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL783799 | 0.83 | CHRM3 (0.54) | CHRM2CHRM3 | |
| SCHEMBL645002 | 0.82 | CHRM2 (0.62) | CHRM2CHRM3 | |
| SCHEMBL783853 | 0.82 | CHRM3 (0.58) | CHRM2CHRM3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | CHRM2 2/4885CHRM3 1/4885SLC2A1 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.