SCHEMBL7995685

SCHEMBL7995685

[N-]=[N+]=C1C=CC(=O)c2cc3ccccc3cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.41
MAOB P27338 2/20 0.41
IDO1 P14902 2/20 0.41
MAOA P21397 1/20 0.41
AKT1 P31749 1/20 0.41
SNCA P37840 1/20 0.41
MAP2K1 Q02750 1/20 0.41
PIN1 Q13526 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41
NSD1 Q96L73 1/20 0.41
EHMT1 Q9H9B1 1/20 0.41
NQO1 P15559 1/20 0.41
TOP1 P11387 1/20 0.36
ALDH1A1 P00352 5/20 0.35
HPGD P15428 4/20 0.35
TP53 P04637 3/20 0.35
MEN1 O00255 3/20 0.35
LMNA P02545 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534567 0.82 CDC25B (0.60) CDC25BMAOBIDO1MAOAAKT1
SCHEMBL449382 0.82 CDC25B (0.60) CDC25BMAOBIDO1MAOAAKT1
Ammonia Solution, Strong SCHEMBL28326620 0.80 CDC25B (0.57) CDC25BMAOBIDO1MAOAAKT1
SCHEMBL27549226 0.78 CDC25B (0.55) CDC25BMAOBIDO1MAOAAKT1
SCHEMBL7654790 0.78 CDC25B (0.55) CDC25BMAOBIDO1MAOAAKT1
SCHEMBL10531324 0.74 CDC25B (0.50) CDC25BMAOBIDO1MAOAAKT1
Anthracene SCHEMBL11125352 0.71 CDC25B (0.74) CDC25BMAOBIDO1MAOAAKT1
SCHEMBL10938543 0.70 IDO1 (0.50) CDC25BMAOBIDO1MAOAAKT1
Naphthoquinone SCHEMBL27843680 0.69 CDC25B (0.70) CDC25BMAOBIDO1MAOAAKT1
Naphthoquinone SCHEMBL29458764 0.68 IDO1 (0.78) CDC25BMAOBIDO1MAOAAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017997-A1 SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY DIAZANS LIMITED (CA) 2001-03-15 WO claimed
WO-2001017997-A1 SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY DIAZANS LIMITED (CA) 2001-03-15 WO disclosed