Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 7/20 | 0.64 |
| ▸ | SELE | P16581 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996192 | 1.00 | SELP (0.64) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL7993235 | 0.94 | SELP (0.63) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL7993244 | 0.94 | SELP (0.63) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL8286561 | 0.91 | SELP (0.76) | SELPSELEPTPN1 | |
| SCHEMBL7996515 | 0.90 | SELP (0.61) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL7992892 | 0.88 | SELP (0.83) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL7996462 | 0.88 | SELP (0.83) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL8196071 | 0.88 | SELP (0.54) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL8196065 | 0.88 | SELP (0.54) | SELPSELEMEN1KMT2AITGB3 | |
| SCHEMBL7995405 | 0.86 | SELP (0.67) | SELPSELEMEN1KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2000033836-A1 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |