Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.67 |
| ▸ | FYN | P06241 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | AHR | P35869 | 2/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851768 | 0.83 | CYP1A2 (0.74) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL4854001 | 0.83 | CYP1A2 (0.74) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL4852478 | 0.83 | CYP1A2 (0.96) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL4853221 | 0.81 | CYP1A2 (0.78) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL4856361 | 0.81 | CYP1A2 (0.70) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL28185455 | 0.81 | CYP1A2 (0.48) | CYP1A2FYNACHEAHRERBB2 | |
| Benzo[Def]Chrysene SCHEMBL23414475 | 0.81 | CYP1A2 (1.00) | CYP1A2FYNACHEAHRERBB2 | |
| Benzo[Def]Chrysene SCHEMBL24019 | 0.81 | CYP1A2 (1.00) | CYP1A2FYNACHEAHRERBB2 | |
| Benzo[Def]Chrysene SCHEMBL17114373 | 0.81 | CYP1A2 (1.00) | CYP1A2FYNACHEAHRERBB2 | |
| Benzo[Def]Chrysene SCHEMBL29352452 | 0.81 | CYP1A2 (1.00) | CYP1A2FYNACHEAHRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |